Category: Food and Nutrition

Food and Nutrition

Diagnostic Stewardship Program: Children With CNS Infection

For a study, researchers sought to determine the best way to implement the FilmArray Meningitis Encephalitis Panel (MEP) multiplex polymerase chain reaction testing of cerebrospinal fluid (CSF) in children with suspected central nervous system infection, as well as the clinical and financial implications. At Children’s Hospital, pre-post quasi-experimental cohort research was carried out to examine […]

Echocardiography Follow-Up Duration in Kawasaki Disease Patients

For a study, researchers sought to determine the best period of echocardiographic follow-up in individuals with Kawasaki illness who did not have an initial coronary aneurysm. They analyzed the outcomes of follow-up echocardiography in children with Kawasaki illness participating in a children’s hospital’s Prospective Observational Study on Stratified Treatment with Immunoglobulin Plus Steroid Efficacy for […]

Air Pollution & the Risk of Parkinson’s Disease (PD)

Parkinson’s disease, like other neurodegenerative conditions, is characterized by abnormal protein buildup, inflammation, and neuron death. Although certain recognized hereditary risk factors exist, genetics alone cannot explain most cases. As a result, it was critical to identify the environmental elements that impose risk and the processes by which they operate.  Recent epidemiological research has discovered […]

Prenatal exposure to antiseizure medication associated with increased risk of autism and intellectual disability

1. In this population-based cohort study, prenatal exposure to topiramate and valproate monotherapy was associated with increased risk of autism spectrum disorder and intellectual disability. 2. Antiseizure medication duotherapies, with the exception of lamotrigine with levetiracetam, were associated with neurodevelopmental disorders. Evidence Rating Level: 2 (Good) Study Rundown: Antiseizure medication (ASM) is a mainstay treatment […]

Rare APOE missense variants V236E and R251G associated with substantial reduction in risk of Alzheimer disease

1. APOE ε3 (V236E) and APOE ε4 (R251G), 2 rare missense genetic variants, both had a substantial association with reducing the risk of Alzheimer disease. 2. These findings further validated the protective effect of the V236E variant and has revealed a novel protective missense variant on APOE ε4. Evidence Rating Level: 3 (Average) Study Rundown: […]

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